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Image Search Results
Journal: MedComm
Article Title: Hsa‐miR‐335 enhances cell migration and invasion in lung adenocarcinoma through targeting Copine‐1
doi: 10.1002/mco2.93
Figure Lengend Snippet: miR‐335 inhibitor suppresses cancer metastasis in vivo. (A) The establishment of miR‐335 stabling knockdown cell line, qRT‐PCR assay detected the expression level of miR‐335 in A549‐luci cells stabling expressing miR‐335 inhibitor. (B) Experimental scheme illustrating the animal experiment design. (C‐D) Bioluminescence imaging and quantification of lung metastasis in the NCG mice that were intravenously injected with A549‐luci cells expressing miR‐335 inhibitor or NC. The lungs were excised for bioluminescence imaging and quantification (E), and the metastatic nodules in lungs were quantified (F). Scale bar, 0.5 cm. The pulmonary metastases in the mouse model were histologically analyzed by H&E staining (G) and CPNE1 staining (H). Bars, SD; * P < 0.05; *** P < 0.001. Dashed circle, metastatic nodules.
Article Snippet:
Techniques: In Vivo, Knockdown, Quantitative RT-PCR, Expressing, Imaging, Injection, Staining